Lipids and sterols in whole grains

Whole grain foods form the foundation of
a healthy diet, and researchers from the
Harvard School of Public Health and the
U.S. Department of Agriculture want us to
eat more of them. That’s the message
being delivered these days as the latest
science reaffirms that whole grains are key
components to a healthy diet. In addition
to providing complex carbohydrates,
whole grains are excellent sources of fiber,
valuable lipids and sterols, and key
vitamins and minerals that are not
available from other sources. Here’s the
problem: The great majority of people
aren’t getting nearly enough of these critical
nutrients!

Recently, the Harvard School of Public
Health re-emphasized the importance of
whole grains by making three serious
changes to the USDA’s Food Guide
Pyramid.1
1. They moved simple, starchy foods—
such as white bread, potatoes, white
rice, and pasta—from the most
important level, the base, to the least
important, the top.
2. They reaffirmed the importance of still
eating six to nine servings from the
base level each day.
3. They stressed the importance of at least
three of those servings being whole
grains, each and every day!
Two facts are behind all the hubbub
about whole grains.
First, whole grains provide critical nutrients
that are not available from other food
sources. In addition to providing key
nutrients like vitamins, minerals, and
fiber, whole grains are also a valuable
source of lipids and sterols, the energygiving
substances that have a direct influence
on cellular health and efficiency.
Unfortunately, lipids and sterols are
often removed from grains through standard
food processing. In an attempt to
reduce food spoilage, for example, lipids
are removed from most cereals, breads,
and flour.Without these essential food
factors, cell membrane function can
become compromised, making it difficult
for nutrients to get in and waste to get
out. Remember, we’re only as healthy as
our cells!
Second, in their report titled “Healthy
People 2010,” USDA researchers state that
only 7% of the population 2 years of age
and older get the three servings of whole
grain daily that are fundamental to good
health.2 This lack of whole grains, and
the lipids and sterols they contain, has
become the single most common deficiency
in the modern diet. According to a
VOLUME # 005
Continued on page 2
USA & CANADA

Scientists Push To Increase
Whole Grains In Diet!
More than a decade ago, the USDA established a
Food Guide Pyramid with a foundation level of
bread, cereal, rice, and pasta. These foods
provide carbohydrates, which are essential to
a sound diet.1 Over time, though, the
importance of these food factors has been
downplayed, or even completely misreported.
Currently, for example, the media is flooded
with information suggesting that carbohydrates
are detrimental to weight management and
good health. But people who buy into the
“low-carb” craze may be denying themselves
important nutrients. It’s true that today’s
consumers need to be smart about the types
and amounts of carbohydrates they eat—but
they also need to make sure they’re getting the
healthy benefits of whole grain. That’s why
many nutrition and healthcare professionals are
working to open our eyes to the importance of
these critical nutrients and suggesting that—
though we should watch our carbs—we also
need to make sure we get a minimum of three
servings of whole grains each day.

LOOK TO THE PYRAMID & BE SMART ABOUT “CARB” CHOICES!
recent article in the Journal of Nutrition,
increased intake of whole-grain foods is
limited by a lack of consumer awareness
of the health benefits of whole grains, difficulty
in identifying whole-grain foods in
the market place, and higher prices for
whole-grain foods.3
Tre-en-en: 3-a-day is the healthy way.
GNLD has long been familiar with the
importance of whole grains and the
unique nutrients they provide to the diet,
and this latest round of scientific reports
strongly reinforces our position. For
over 46 years, we have known that good
nutrition begins at the cellular level,
and that whole grain lipids and sterols
contribute critical factors to optimal cellular
nutrition, helping to keep cell membranes
healthy, permeable, and efficient—
able to take in nutrients and eliminate
waste and be their energetic best.
In 1958, scientists formulated a dietary
supplement that replaces the lipids and
sterols lost through food processing and a
whole-grain-deficient diet. This supplement
became known as Tre-en-en Grain
Concentrates, a unique combination of
concentrated extracts from wheat, rice
bran, and soybeans, tested and proven to
enhance cellular efficiency. Its importance
in the diet today is greater than it has ever
been in the past.
The foundation of the Food Guide
Pyramid is the foundation of your healthy
diet. So work to make sure you eat your 6-
9 servings of this important food group
each day. And just so you are sure you’re
receiving the benefits of the whole-grain
lipids and sterols you need, take three
Tre-en-en each and every day!
Continued from page 1
References
1. www.hsph.harvard.edu
2 www.health.gov
3. “Choose A Variety of Grains Daily, Especially Whole Grains:
A Challenge for Consumers”, Kantor, Linda, et al Journal of
Nutrition, 2001; 131:473S-486S
4. www.usda.gov
5. www.msnbc.com
6. www.fda.gov
7. www.betterhealth.vic.gov.au

Lipids and sterols in tre-en-en

WHY “GRAIN CONCENTRATES”?
■ As grain processing strips away nutrient-dense and
nutrient-diverse outer layers, the foods that make up our
dietary staples (i.e. white flour, white rice) often lack
meaningful amounts of nutrients important for cell
function — namely, lipids and sterols.
■ Soybeans, wheat, and rice provide key lipids and sterols
that are important for cellular health.

WHY TRE-EN-EN GRAIN CONCENTRATES?
■ Diverse phytonutrient extracts supply critical nutrients
cells need to be their healthy best.
■ Scientifically proven to support efficient nutrient
utilization.
■ Scientifically proven to support overall growth and
development.
■ Scientifically proven to support cardiovascular
development.
■ Cold-pressed and cold-processed to preserve nutritional
value.
■ No cholesterol.
■ No gluten.
■ Complete lipids and sterols from wheat germ, rice bran,
and soybeans.
■ Includes beta-sitosterol, gamma-oryzanol, stimasterol, and
campesterol, plus octacosanol.
■ Natural chlorophyll-colored,
soft gelatin capsules.
■ Natural vitamin E for antioxidant protection of
phytonutrients.

FAST FACTS ABOUT TRE-EN-EN®
GRAIN CONCENTRATES
Cell membranes need lipids and sterols to stay healthy. Unfortunately, grain processing strips lipids, sterols, and
other vital nutrients from the foods that make up our dietary staples. Tre-en-en Grain Concentrates help assure
good nutrition at the cellular level by providing a unique and exclusive blend of whole-food extracts from wheat
germ, rice bran, and soybeans. Developed and introduced by GNLD in 1958, Tre-en-en was the world’s first
phytonutrient supplement. It provides phyto-LIPIDS essential to optimal health and cellular function, including
omega-6 and omega-3 fatty acids, and phyto-STEROLS, including beta-sitosterol, gamma-oryzanol, stimasterol,
and campesterol, plus octacosanol.

TRE-EN-EN´® GRAIN CONCENTRATES
Products – 4.06 P-1
SUGGESTED USE: (Adults) 1 capsule daily with meals.
Lipids and sterols provide critical support for the healthy cellular
uptake of nutrients and cellular export of waste and metabolites.*
* This statement has not been evaluated by the Food & Drug
Administration. This product is not intended to diagnose, treat,
cure or prevent any disease.
TRE-EN-EN ® Grain Concentrates "feed your cells" with an exclusive
whole-food blend of extracts from wheat, rice and soy. It provides
phyto-LIPIDS, including Omega-6 and Omega-3 fatty acids, phyto-
STEROLS beta-sitosterol, gamma-oryzanol, stimasterol, and
campesterol, plus octacosanol.
Contains no cholesterol or gluten.
Cold pressed and cold processed to preserve nutritional value.
Store in a cool, dry place, away from direct sunlight.
Packaged with safety seal.
®
NOT SOLD IN RETAIL STORES
Available Exclusively From GNLD Distributors
Distributed by: Golden Neo-Life Diamite International
Fremont, California 94538 U.S.A.
Golden Neo-Life Diamite International, Ltd.
Bridgetown, Barbados, W.I.
Kingston, Jamaica, W.I.
Port of Spain, Trinidad, W.I.
Leading edge nutrition since 1958. Made in U.S.A.
P-2 Products – 2.06
TRE-EN-EN´® GRAIN CONCENTRATES
TRE-EN-EN SUPPLIES WHAT FOOD PROCESSING
STRIPS FROM DIETARY STAPLES
To increase their shelf life, grains are subjected to about two
dozen processes before they are transformed into dietary
staples, such as white flour and white rice. Processing removes
the nutritious outer layers of the grain. These layers contain
the majority of grain’s vitamins and minerals, as well as “good
fats” called lipids and sterols. Other foods, notably soybeans,
provide healthful lipids and sterols as well.
In the 1950s, a series of studies conducted at a Southern
California hospital indicated that people suffering from
chronic fatigue could benefit dramatically from a mixture of
plant extracts providing broad-spectrum lipids and sterols.
Now, more than four decades later, that mixture — GNLD’s
Tre-en-en — is still helping people worldwide. It forms the
base into which vitamins and related food factors, minerals,
enzymes, and protein have been added to create GNLD’s
multifactor food supplement, Formula IV®.
The world’s first phytonutrient supplement, Tre-en-en provides
plant lipids and sterols which food processing has stripped
from the staple foods that form the foundation of our daily
diets. Named for the Greek “3-in-1,” Tre-en-en is a unique
combination of concentrated extracts from whole wheat berry,
rice bran, and soybeans. More than just wheat germ or soy oil, it
contains everything naturally available from the lipid portion
of the plants.
LIPIDS AND STEROLS: BUILDING BLOCKS FOR
EVERY CELL MEMBRANE IN THE HUMAN BODY
When it comes to health, not all fats are bad. Some fats are
good — even essential. Fats provide energy, essential fatty
acids, and cellular building blocks, and they have regulatory
functions. For instance, fats are necessary for normal growth
and development, especially for infants. They are also
important to the structure and function of the nervous system.
But most importantly, they make up the greater part of the
membranes that surround every cell in the human body.
Healthful lipids and sterols from wheat, rice, and soybeans
are “good fats.” Certain lipids, including omega-6 and omega-3
fatty acids, may increase the fluidity, or “pliability,” of cell
membranes and help keep cells functioning normally. Plant
sterols may have a number of beneficial effects as well,
including reducing cholesterol levels, lowering the risk of
atherosclerosis, and inhibiting tumors. Both lipids and sterols
are located in the bran and outer layers which are removed
during grain processing (see The Story of Wheat, The Story of
Rice, and The Story of Soy).
CONSEQUENCES OF THE IMBALANCE OF “GOOD”
AND “BAD” FATS IN THE MODERN DIET
With consumer preferences shifting to low-fat and fat-free
foods, people are eating less fat than in recent years, although
the fat content of the Western diet is still far from the 30%
recommended by health experts. While reducing the fat content
of the diet has many positive health consequences, it means
that people are reducing the total lipids and sterols they are
taking in from all sources, not just “bad” fats such as saturated
fats. They are also reducing their intake of “good” fats from
whole grains and soybeans, which supply important lipid and
sterol nutrients you need to feel your best.
In the quest to reduce the fat content of the diet, fat
substitutes or “fake fats” have begun to make their way into the
marketplace. While these substances may make some foods less
caloric and fatty, they do nothing to meet the body’s hunger
for good nutrition. Whole-food lipids and sterols from wheat,
rice, and soy will be especially important for the growing
group of people who use fat substitutes to reduce the fat
content of their diets.
The decrease in total fat consumption is only part of the
reason the modern diet features an imbalance of “good” and
“bad” fats. The other part of the story is that the foods that
make up the human diet have changed dramatically in the last
50 years. As artificial fats have increasingly displaced natural
fats in the foods we eat, the lipid and sterol profile of the diet
has changed. While our hunter-gatherer ancestors consumed a
diversity of natural fats, mostly from locally gleaned plants,
this diversity decreased when people became successful at
growing agricultural crops which could be sold at the local
farmers’ market. This eroding nutrient diversity was
compounded by a decrease in nutrient density when people
discovered that grains could be stored longer without going
rancid if their lipid- and sterol-rich outer coatings were
removed. And after World War II, the world got its first taste
of margarine and other artificially hydrogenated oils, and the
global kitchen has never been the same. This relatively rapid
displacement of natural fats with artificial fats in all types of
foods has created an unhealthy imbalance of “good” versus
“bad” fats and has diminished the amount and variety of
healthful lipids and sterols in the diet.
Imbalance has consequences: Insufficiency of lipids and
sterols may cause alterations of the cell membrane, leading to
reduced cellular efficiency throughout the body. It may also
affect the ability of the cell’s “metabolic machinery” to
produce energy. Lipid/sterol insufficiency may also slow the
normal workings of the endocrine glands, which virtually

THE TRE-EN-EN® GRAIN
CONCENTRATES STORY
control the body’s energy levels. For these reasons, insufficiency
of lipids and sterols may be a factor in long-term fatigue.
TRE-EN-EN® FOR CELLULAR EFFICIENCY
Our bodies are composed of trillions of cells which must
work efficiently if we are to stay healthy. How do cells stay
healthy? The key is their membranes. Like bodies, cells must
take in nutrients and eliminate wastes. Every cell in the body
is surrounded by a lipid membrane with the discretionary
power to allow only needed nutrients to enter the cell. By the
same token, it allows only waste material and metabolic
products (hormones, enzymes, neurotransmitters, etc.) to exit.
Deficiencies of lipids, sterols, and amino acids can compromise
the discretionary power of cells. Cells can become “starved”
(inhibited in their ability to take in substances) even though
nutrients are available. And they can become “constipated”
(inhibited in their ability to eliminate accumulating waste
products or export metabolites). Under these conditions, cells
work inefficiently, expending more energy than healthy cells
would to get the same results.
Tre-en-en Grain Concentrates supply essential lipids and
sterols to promote the efficient functioning of cells, glandular
systems, and the entire body. Remember, we are only as healthy
as our cells, and Tre-en-en strengthens the lipid/sterol “link” in
our “Chain of Life,” supporting cellular health and vitality.

PROVEN EFFECTIVE IN LABORATORY TESTS
Scientists have known for years that lipids and sterols are
required for normal cellular functioning, glandular activity,
and overall growth and development. A series of studies
conducted at Texas A&M University in 1987 confirmed the
nutritional benefits of Tre-en-en Grain Concentrates (lipids
and sterols from wheat, rice, and soybeans). The seven-week
studies looked at growth, development, maturation, and
glandular activity of young rats fed either a standard control
diet (laboratory chow fortified with vitamins and minerals) or
the standard diet with Tre-en-en Grain Concentrates
substituted for the lipids used in the standard chow. Animals
were allowed to eat as much as they wanted; both chows had
the same caloric content. (All tests were performed and all
animals were housed and cared for with the highest level of
concern for the health and well being of the animals. No
animals were exposed to conditions of pain or suffering.)
When the amount of food consumed was correlated with
the amount of weight the rats gained, the researchers found
that the Tre-en-en-fed animals displayed superior growth and
development, indicating that their bodies made better use of
the available nutrients. In all cases the Tre-en-en-fed group
grew faster, achieved maturity faster, and had better overall
development than the group that was fed the control diet. In
addition, the cardiovascular systems of the Tre-en-en-fed group
were better developed, and their adrenal activity — an
indicator of their energy levels and ability to respond to stress
— was greater.
OVERALL GROWTH AND DEVELOPMENT
Animals fed diets fortified with Tre-en-en Grain
Concentrates attained a greater level of overall growth and
development than did animals fed a control diet.

CARDIOVASCULAR DEVELOPMENT
Animals on the Tre-en-en diet displayed greater
cardiovascular development than did animals fed the control
diet. Cardiovascular development (measured by heart weight)
paralleled overall growth and development, indicating that
larger animals were not “fatter” but instead were more fully
developed.
NUTRIENT UTILIZATION EFFICIENCY
Compared to animals on a control diet, the animals fed Treen-
en Grain Concentrates demonstrated superior growth,
development, and maturation, even though each test group
consumed the same amount of calories. This result indicates
that the Tre-en-en-fed animals utilized nutrients from food
more efficiently than did control animals.
TRE-EN-EN´® GRAIN CONCENTRATES
Products – 4.06 P-3
P-4 Products – 6.05
TRE-EN-EN´® GRAIN CONCENTRATES
GLANDULAR ACTIVITY
Glandular activity (as measured by liver glycogen levels) was
almost twice as high in the Tre-en-en-fed rats compared to the
control animals. This result indicates that the Tre-en-en-fed
animals had higher energy levels and were better prepared to
handle stress.
Unique and exclusively available from GNLD, Tre-en-en
provides lipids and sterols cells need to be their healthy best!
With cold-pressed, cold-processed extracts and concentrates
from wheat germ, rice bran, and soybeans, Tre-en-en helps
assure good nutrition at the cellular level.

Tre-en-en wholegrain supplements

WHY “GRAIN CONCENTRATES”?

■ As grain processing strips away nutrient-dense and
nutrient-diverse outer layers, the foods that make up our
dietary staples (i.e. white flour, white rice) often lack
meaningful amounts of nutrients important for cell
function — namely, lipids and sterols.
■ Soybeans, wheat, and rice provide key lipids and sterols
that are important for cellular health.

WHY TRE-EN-EN GRAIN CONCENTRATES?
■ Diverse phytonutrient extracts supply critical nutrients
cells need to be their healthy best.
■ Scientifically proven to support efficient nutrient
utilization.
■ Scientifically proven to support overall growth and
development.
■ Scientifically proven to support cardiovascular
development.
■ Cold-pressed and cold-processed to preserve nutritional
value.
■ No cholesterol.
■ No gluten.
■ Complete lipids and sterols from wheat germ, rice bran,
and soybeans.
■ Includes beta-sitosterol, gamma-oryzanol, stimasterol, and
campesterol, plus octacosanol.
■ Natural chlorophyll-colored,
soft gelatin capsules.
■ Natural vitamin E for antioxidant protection of
phytonutrients.

FAST FACTS ABOUT TRE-EN-EN®
GRAIN CONCENTRATES
Cell membranes need lipids and sterols to stay healthy. Unfortunately, grain processing strips lipids, sterols, and
other vital nutrients from the foods that make up our dietary staples. Tre-en-en Grain Concentrates help assure
good nutrition at the cellular level by providing a unique and exclusive blend of whole-food extracts from wheat
germ, rice bran, and soybeans. Developed and introduced by GNLD in 1958, Tre-en-en was the world’s first
phytonutrient supplement. It provides phyto-LIPIDS essential to optimal health and cellular function, including
omega-6 and omega-3 fatty acids, and phyto-STEROLS, including beta-sitosterol, gamma-oryzanol, stimasterol,
and campesterol, plus octacosanol.

TRE-EN-EN´® GRAIN CONCENTRATES
Products – 4.06 P-1
SUGGESTED USE: (Adults) 1 capsule daily with meals.
Lipids and sterols provide critical support for the healthy cellular
uptake of nutrients and cellular export of waste and metabolites.*
* This statement has not been evaluated by the Food & Drug
Administration. This product is not intended to diagnose, treat,
cure or prevent any disease.
TRE-EN-EN ® Grain Concentrates "feed your cells" with an exclusive
whole-food blend of extracts from wheat, rice and soy. It provides
phyto-LIPIDS, including Omega-6 and Omega-3 fatty acids, phyto-
STEROLS beta-sitosterol, gamma-oryzanol, stimasterol, and
campesterol, plus octacosanol.
Contains no cholesterol or gluten.
Cold pressed and cold processed to preserve nutritional value.
Store in a cool, dry place, away from direct sunlight.
Packaged with safety seal.
®
NOT SOLD IN RETAIL STORES
Available Exclusively From GNLD Distributors
Distributed by: Golden Neo-Life Diamite International
Fremont, California 94538 U.S.A.
Golden Neo-Life Diamite International, Ltd.
Bridgetown, Barbados, W.I.
Kingston, Jamaica, W.I.
Port of Spain, Trinidad, W.I.
Leading edge nutrition since 1958. Made in U.S.A.
P-2 Products – 2.06
TRE-EN-EN´® GRAIN CONCENTRATES
TRE-EN-EN SUPPLIES WHAT FOOD PROCESSING
STRIPS FROM DIETARY STAPLES
To increase their shelf life, grains are subjected to about two
dozen processes before they are transformed into dietary
staples, such as white flour and white rice. Processing removes
the nutritious outer layers of the grain. These layers contain
the majority of grain’s vitamins and minerals, as well as “good
fats” called lipids and sterols. Other foods, notably soybeans,
provide healthful lipids and sterols as well.
In the 1950s, a series of studies conducted at a Southern
California hospital indicated that people suffering from
chronic fatigue could benefit dramatically from a mixture of
plant extracts providing broad-spectrum lipids and sterols.
Now, more than four decades later, that mixture — GNLD’s
Tre-en-en — is still helping people worldwide. It forms the
base into which vitamins and related food factors, minerals,
enzymes, and protein have been added to create GNLD’s
multifactor food supplement, Formula IV®.
The world’s first phytonutrient supplement, Tre-en-en provides
plant lipids and sterols which food processing has stripped
from the staple foods that form the foundation of our daily
diets. Named for the Greek “3-in-1,” Tre-en-en is a unique
combination of concentrated extracts from whole wheat berry,
rice bran, and soybeans. More than just wheat germ or soy oil, it
contains everything naturally available from the lipid portion
of the plants.

LIPIDS AND STEROLS: BUILDING BLOCKS FOR
EVERY CELL MEMBRANE IN THE HUMAN BODY
When it comes to health, not all fats are bad. Some fats are
good — even essential. Fats provide energy, essential fatty
acids, and cellular building blocks, and they have regulatory
functions. For instance, fats are necessary for normal growth
and development, especially for infants. They are also
important to the structure and function of the nervous system.
But most importantly, they make up the greater part of the
membranes that surround every cell in the human body.
Healthful lipids and sterols from wheat, rice, and soybeans
are “good fats.” Certain lipids, including omega-6 and omega-3
fatty acids, may increase the fluidity, or “pliability,” of cell
membranes and help keep cells functioning normally. Plant
sterols may have a number of beneficial effects as well,
including reducing cholesterol levels, lowering the risk of
atherosclerosis, and inhibiting tumors. Both lipids and sterols
are located in the bran and outer layers which are removed
during grain processing (see The Story of Wheat, The Story of
Rice, and The Story of Soy).

CONSEQUENCES OF THE IMBALANCE OF “GOOD”
AND “BAD” FATS IN THE MODERN DIET
With consumer preferences shifting to low-fat and fat-free
foods, people are eating less fat than in recent years, although
the fat content of the Western diet is still far from the 30%
recommended by health experts. While reducing the fat content
of the diet has many positive health consequences, it means
that people are reducing the total lipids and sterols they are
taking in from all sources, not just “bad” fats such as saturated
fats. They are also reducing their intake of “good” fats from
whole grains and soybeans, which supply important lipid and
sterol nutrients you need to feel your best.
In the quest to reduce the fat content of the diet, fat
substitutes or “fake fats” have begun to make their way into the
marketplace. While these substances may make some foods less
caloric and fatty, they do nothing to meet the body’s hunger
for good nutrition. Whole-food lipids and sterols from wheat,
rice, and soy will be especially important for the growing
group of people who use fat substitutes to reduce the fat
content of their diets.
The decrease in total fat consumption is only part of the
reason the modern diet features an imbalance of “good” and
“bad” fats. The other part of the story is that the foods that
make up the human diet have changed dramatically in the last
50 years. As artificial fats have increasingly displaced natural
fats in the foods we eat, the lipid and sterol profile of the diet
has changed. While our hunter-gatherer ancestors consumed a
diversity of natural fats, mostly from locally gleaned plants,
this diversity decreased when people became successful at
growing agricultural crops which could be sold at the local
farmers’ market. This eroding nutrient diversity was
compounded by a decrease in nutrient density when people
discovered that grains could be stored longer without going
rancid if their lipid- and sterol-rich outer coatings were
removed. And after World War II, the world got its first taste
of margarine and other artificially hydrogenated oils, and the
global kitchen has never been the same. This relatively rapid
displacement of natural fats with artificial fats in all types of
foods has created an unhealthy imbalance of “good” versus
“bad” fats and has diminished the amount and variety of
healthful lipids and sterols in the diet.
Imbalance has consequences: Insufficiency of lipids and
sterols may cause alterations of the cell membrane, leading to
reduced cellular efficiency throughout the body. It may also
affect the ability of the cell’s “metabolic machinery” to
produce energy. Lipid/sterol insufficiency may also slow the
normal workings of the endocrine glands, which virtually

THE TRE-EN-EN® GRAIN
CONCENTRATES STORY
control the body’s energy levels. For these reasons, insufficiency
of lipids and sterols may be a factor in long-term fatigue.
TRE-EN-EN® FOR CELLULAR EFFICIENCY
Our bodies are composed of trillions of cells which must
work efficiently if we are to stay healthy. How do cells stay
healthy? The key is their membranes. Like bodies, cells must
take in nutrients and eliminate wastes. Every cell in the body
is surrounded by a lipid membrane with the discretionary
power to allow only needed nutrients to enter the cell. By the
same token, it allows only waste material and metabolic
products (hormones, enzymes, neurotransmitters, etc.) to exit.
Deficiencies of lipids, sterols, and amino acids can compromise
the discretionary power of cells. Cells can become “starved”
(inhibited in their ability to take in substances) even though
nutrients are available. And they can become “constipated”
(inhibited in their ability to eliminate accumulating waste
products or export metabolites). Under these conditions, cells
work inefficiently, expending more energy than healthy cells
would to get the same results.
Tre-en-en Grain Concentrates supply essential lipids and
sterols to promote the efficient functioning of cells, glandular
systems, and the entire body. Remember, we are only as healthy
as our cells, and Tre-en-en strengthens the lipid/sterol “link” in
our “Chain of Life,” supporting cellular health and vitality.

PROVEN EFFECTIVE IN LABORATORY TESTS
Scientists have known for years that lipids and sterols are
required for normal cellular functioning, glandular activity,
and overall growth and development. A series of studies
conducted at Texas A&M University in 1987 confirmed the
nutritional benefits of Tre-en-en Grain Concentrates (lipids
and sterols from wheat, rice, and soybeans). The seven-week
studies looked at growth, development, maturation, and
glandular activity of young rats fed either a standard control
diet (laboratory chow fortified with vitamins and minerals) or
the standard diet with Tre-en-en Grain Concentrates
substituted for the lipids used in the standard chow. Animals
were allowed to eat as much as they wanted; both chows had
the same caloric content. (All tests were performed and all
animals were housed and cared for with the highest level of
concern for the health and well being of the animals. No
animals were exposed to conditions of pain or suffering.)
When the amount of food consumed was correlated with
the amount of weight the rats gained, the researchers found
that the Tre-en-en-fed animals displayed superior growth and
development, indicating that their bodies made better use of
the available nutrients. In all cases the Tre-en-en-fed group
grew faster, achieved maturity faster, and had better overall
development than the group that was fed the control diet. In
addition, the cardiovascular systems of the Tre-en-en-fed group
were better developed, and their adrenal activity — an
indicator of their energy levels and ability to respond to stress
— was greater.

OVERALL GROWTH AND DEVELOPMENT
Animals fed diets fortified with Tre-en-en Grain
Concentrates attained a greater level of overall growth and
development than did animals fed a control diet.
CARDIOVASCULAR DEVELOPMENT
Animals on the Tre-en-en diet displayed greater
cardiovascular development than did animals fed the control
diet. Cardiovascular development (measured by heart weight)
paralleled overall growth and development, indicating that
larger animals were not “fatter” but instead were more fully
developed.
NUTRIENT UTILIZATION EFFICIENCY
Compared to animals on a control diet, the animals fed Treen-
en Grain Concentrates demonstrated superior growth,
development, and maturation, even though each test group
consumed the same amount of calories. This result indicates
that the Tre-en-en-fed animals utilized nutrients from food
more efficiently than did control animals.
TRE-EN-EN´® GRAIN CONCENTRATES
Products – 4.06 P-3
P-4 Products – 6.05

TRE-EN-EN´® GRAIN CONCENTRATES
GLANDULAR ACTIVITY
Glandular activity (as measured by liver glycogen levels) was
almost twice as high in the Tre-en-en-fed rats compared to the
control animals. This result indicates that the Tre-en-en-fed
animals had higher energy levels and were better prepared to
handle stress.
Unique and exclusively available from GNLD, Tre-en-en
provides lipids and sterols cells need to be their healthy best!
With cold-pressed, cold-processed extracts and concentrates
from wheat germ, rice bran, and soybeans, Tre-en-en helps
assure good nutrition at the cellular level.

Tre-en-en whole grain concentrates

WHY “GRAIN CONCENTRATES”?

■ As grain processing strips away nutrient-dense and
nutrient-diverse outer layers, the foods that make up our
dietary staples (i.e. white flour, white rice) often lack
meaningful amounts of nutrients important for cell
function — namely, lipids and sterols.
■ Soybeans, wheat, and rice provide key lipids and sterols
that are important for cellular health.
WHY TRE-EN-EN GRAIN CONCENTRATES?
■ Diverse phytonutrient extracts supply critical nutrients
cells need to be their healthy best.
■ Scientifically proven to support efficient nutrient
utilization.
■ Scientifically proven to support overall growth and
development.
■ Scientifically proven to support cardiovascular
development.
■ Cold-pressed and cold-processed to preserve nutritional
value.
■ No cholesterol.
■ No gluten.
■ Complete lipids and sterols from wheat germ, rice bran,
and soybeans.
■ Includes beta-sitosterol, gamma-oryzanol, stimasterol, and
campesterol, plus octacosanol.
■ Natural chlorophyll-colored,
soft gelatin capsules.
■ Natural vitamin E for antioxidant protection of
phytonutrients.
FAST FACTS ABOUT TRE-EN-EN®
GRAIN CONCENTRATES

Cell membranes need lipids and sterols to stay healthy. Unfortunately, grain processing strips lipids, sterols, and
other vital nutrients from the foods that make up our dietary staples. Tre-en-en Grain Concentrates help assure
good nutrition at the cellular level by providing a unique and exclusive blend of whole-food extracts from wheat
germ, rice bran, and soybeans. Developed and introduced by GNLD in 1958, Tre-en-en was the world’s first
phytonutrient supplement. It provides phyto-LIPIDS essential to optimal health and cellular function, including
omega-6 and omega-3 fatty acids, and phyto-STEROLS, including beta-sitosterol, gamma-oryzanol, stimasterol,
and campesterol, plus octacosanol.
TRE-EN-EN´® GRAIN CONCENTRATES
Products – 4.06 P-1
SUGGESTED USE: (Adults) 1 capsule daily with meals.
Lipids and sterols provide critical support for the healthy cellular
uptake of nutrients and cellular export of waste and metabolites.*
* This statement has not been evaluated by the Food & Drug
Administration. This product is not intended to diagnose, treat,
cure or prevent any disease.
TRE-EN-EN ® Grain Concentrates "feed your cells" with an exclusive
whole-food blend of extracts from wheat, rice and soy. It provides
phyto-LIPIDS, including Omega-6 and Omega-3 fatty acids, phyto-
STEROLS beta-sitosterol, gamma-oryzanol, stimasterol, and
campesterol, plus octacosanol.
Contains no cholesterol or gluten.
Cold pressed and cold processed to preserve nutritional value.
Store in a cool, dry place, away from direct sunlight.
Packaged with safety seal.
®
NOT SOLD IN RETAIL STORES

Available Exclusively From GNLD Distributors
Distributed by: Golden Neo-Life Diamite International
Fremont, California 94538 U.S.A.
Golden Neo-Life Diamite International, Ltd.
Bridgetown, Barbados, W.I.
Kingston, Jamaica, W.I.
Port of Spain, Trinidad, W.I.
Leading edge nutrition since 1958. Made in U.S.A.
P-2 Products – 2.06
TRE-EN-EN´® GRAIN CONCENTRATES
TRE-EN-EN SUPPLIES WHAT FOOD PROCESSING
STRIPS FROM DIETARY STAPLES

To increase their shelf life, grains are subjected to about two
dozen processes before they are transformed into dietary
staples, such as white flour and white rice. Processing removes
the nutritious outer layers of the grain. These layers contain
the majority of grain’s vitamins and minerals, as well as “good
fats” called lipids and sterols. Other foods, notably soybeans,
provide healthful lipids and sterols as well.
In the 1950s, a series of studies conducted at a Southern
California hospital indicated that people suffering from
chronic fatigue could benefit dramatically from a mixture of
plant extracts providing broad-spectrum lipids and sterols.
Now, more than four decades later, that mixture — GNLD’s
Tre-en-en — is still helping people worldwide. It forms the
base into which vitamins and related food factors, minerals,
enzymes, and protein have been added to create GNLD’s
multifactor food supplement, Formula IV®.
The world’s first phytonutrient supplement, Tre-en-en provides
plant lipids and sterols which food processing has stripped
from the staple foods that form the foundation of our daily
diets. Named for the Greek “3-in-1,” Tre-en-en is a unique
combination of concentrated extracts from whole wheat berry,
rice bran, and soybeans. More than just wheat germ or soy oil, it
contains everything naturally available from the lipid portion
of the plants.
LIPIDS AND STEROLS: BUILDING BLOCKS FOR
EVERY CELL MEMBRANE IN THE HUMAN BODY

When it comes to health, not all fats are bad. Some fats are
good — even essential. Fats provide energy, essential fatty
acids, and cellular building blocks, and they have regulatory
functions. For instance, fats are necessary for normal growth
and development, especially for infants. They are also
important to the structure and function of the nervous system.
But most importantly, they make up the greater part of the
membranes that surround every cell in the human body.
Healthful lipids and sterols from wheat, rice, and soybeans
are “good fats.” Certain lipids, including omega-6 and omega-3
fatty acids, may increase the fluidity, or “pliability,” of cell
membranes and help keep cells functioning normally. Plant
sterols may have a number of beneficial effects as well,
including reducing cholesterol levels, lowering the risk of
atherosclerosis, and inhibiting tumors. Both lipids and sterols
are located in the bran and outer layers which are removed
during grain processing (see The Story of Wheat, The Story of
Rice, and The Story of Soy).

CONSEQUENCES OF THE IMBALANCE OF “GOOD”
AND “BAD” FATS IN THE MODERN DIET

With consumer preferences shifting to low-fat and fat-free
foods, people are eating less fat than in recent years, although
the fat content of the Western diet is still far from the 30%
recommended by health experts. While reducing the fat content
of the diet has many positive health consequences, it means
that people are reducing the total lipids and sterols they are
taking in from all sources, not just “bad” fats such as saturated
fats. They are also reducing their intake of “good” fats from
whole grains and soybeans, which supply important lipid and
sterol nutrients you need to feel your best.
In the quest to reduce the fat content of the diet, fat
substitutes or “fake fats” have begun to make their way into the
marketplace. While these substances may make some foods less
caloric and fatty, they do nothing to meet the body’s hunger
for good nutrition. Whole-food lipids and sterols from wheat,
rice, and soy will be especially important for the growing
group of people who use fat substitutes to reduce the fat
content of their diets.
The decrease in total fat consumption is only part of the
reason the modern diet features an imbalance of “good” and
“bad” fats. The other part of the story is that the foods that
make up the human diet have changed dramatically in the last
50 years. As artificial fats have increasingly displaced natural
fats in the foods we eat, the lipid and sterol profile of the diet
has changed. While our hunter-gatherer ancestors consumed a
diversity of natural fats, mostly from locally gleaned plants,
this diversity decreased when people became successful at
growing agricultural crops which could be sold at the local
farmers’ market. This eroding nutrient diversity was
compounded by a decrease in nutrient density when people
discovered that grains could be stored longer without going
rancid if their lipid- and sterol-rich outer coatings were
removed. And after World War II, the world got its first taste
of margarine and other artificially hydrogenated oils, and the
global kitchen has never been the same. This relatively rapid
displacement of natural fats with artificial fats in all types of
foods has created an unhealthy imbalance of “good” versus
“bad” fats and has diminished the amount and variety of
healthful lipids and sterols in the diet.
Imbalance has consequences: Insufficiency of lipids and
sterols may cause alterations of the cell membrane, leading to
reduced cellular efficiency throughout the body. It may also
affect the ability of the cell’s “metabolic machinery” to
produce energy. Lipid/sterol insufficiency may also slow the
normal workings of the endocrine glands, which virtually
THE TRE-EN-EN® GRAIN
CONCENTRATES STORY

control the body’s energy levels. For these reasons, insufficiency
of lipids and sterols may be a factor in long-term fatigue.
TRE-EN-EN® FOR CELLULAR EFFICIENCY
Our bodies are composed of trillions of cells which must
work efficiently if we are to stay healthy. How do cells stay
healthy? The key is their membranes. Like bodies, cells must
take in nutrients and eliminate wastes. Every cell in the body
is surrounded by a lipid membrane with the discretionary
power to allow only needed nutrients to enter the cell. By the
same token, it allows only waste material and metabolic
products (hormones, enzymes, neurotransmitters, etc.) to exit.
Deficiencies of lipids, sterols, and amino acids can compromise
the discretionary power of cells. Cells can become “starved”
(inhibited in their ability to take in substances) even though
nutrients are available. And they can become “constipated”
(inhibited in their ability to eliminate accumulating waste
products or export metabolites). Under these conditions, cells
work inefficiently, expending more energy than healthy cells
would to get the same results.
Tre-en-en Grain Concentrates supply essential lipids and
sterols to promote the efficient functioning of cells, glandular
systems, and the entire body. Remember, we are only as healthy
as our cells, and Tre-en-en strengthens the lipid/sterol “link” in
our “Chain of Life,” supporting cellular health and vitality.

PROVEN EFFECTIVE IN LABORATORY TESTS

Scientists have known for years that lipids and sterols are
required for normal cellular functioning, glandular activity,
and overall growth and development. A series of studies
conducted at Texas A&M University in 1987 confirmed the
nutritional benefits of Tre-en-en Grain Concentrates (lipids
and sterols from wheat, rice, and soybeans). The seven-week
studies looked at growth, development, maturation, and
glandular activity of young rats fed either a standard control
diet (laboratory chow fortified with vitamins and minerals) or
the standard diet with Tre-en-en Grain Concentrates
substituted for the lipids used in the standard chow. Animals
were allowed to eat as much as they wanted; both chows had
the same caloric content. (All tests were performed and all
animals were housed and cared for with the highest level of
concern for the health and well being of the animals. No
animals were exposed to conditions of pain or suffering.)
When the amount of food consumed was correlated with
the amount of weight the rats gained, the researchers found
that the Tre-en-en-fed animals displayed superior growth and
development, indicating that their bodies made better use of
the available nutrients. In all cases the Tre-en-en-fed group
grew faster, achieved maturity faster, and had better overall
development than the group that was fed the control diet. In
addition, the cardiovascular systems of the Tre-en-en-fed group
were better developed, and their adrenal activity — an
indicator of their energy levels and ability to respond to stress
— was greater.

OVERALL GROWTH AND DEVELOPMENT
Animals fed diets fortified with Tre-en-en Grain
Concentrates attained a greater level of overall growth and
development than did animals fed a control diet.
CARDIOVASCULAR DEVELOPMENT
Animals on the Tre-en-en diet displayed greater
cardiovascular development than did animals fed the control
diet. Cardiovascular development (measured by heart weight)
paralleled overall growth and development, indicating that
larger animals were not “fatter” but instead were more fully
developed.

NUTRIENT UTILIZATION EFFICIENCY
Compared to animals on a control diet, the animals fed Treen-
en Grain Concentrates demonstrated superior growth,
development, and maturation, even though each test group
consumed the same amount of calories. This result indicates
that the Tre-en-en-fed animals utilized nutrients from food
more efficiently than did control animals.
TRE-EN-EN´® GRAIN CONCENTRATES
Products – 4.06 P-3
P-4 Products – 6.05
TRE-EN-EN´® GRAIN CONCENTRATES
GLANDULAR ACTIVITY
Glandular activity (as measured by liver glycogen levels) was
almost twice as high in the Tre-en-en-fed rats compared to the
control animals. This result indicates that the Tre-en-en-fed
animals had higher energy levels and were better prepared to
handle stress.
Unique and exclusively available from GNLD, Tre-en-en
provides lipids and sterols cells need to be their healthy best!
With cold-pressed, cold-processed extracts and concentrates
from wheat germ, rice bran, and soybeans, Tre-en-en helps
assure good nutrition at the cellular level.

Salmon oil+ (omega 3)

WHY SUPPLEMENT WITH FISH OIL RICH IN
OMEGA-3 FATTY ACIDS?
■ Fatty fish is the richest source of healthful omega-3 fatty
acids, but most of us do not eat the 2-3 servings per week
that experts recommend for optimal health.
■ Supplementation has been proven to be an effective means
of increasing dietary omega-3 fatty acids.
■ Omega-3 fatty acids support optimal function of body
tissues and organs, notably the heart, blood vessels, brain,
nerves, eyes, skin and joints.
■ Omega-3 fatty acids may prohibit overproduction of
substances that cause inflammation and contribute to
arthritis, menstrual pain, psoriasis, inflamed bowel and
other conditions.
■ Omega-3 fatty acids, crucial to the development of infant
brain and eyes, are naturally present in mother’s milk.
Infants, whose mothers consume foods rich in omega-3
fatty acids, have higher omega-3 fatty acid levels compared
to those whose mothers do not consume omega-3-rich
foods.
■ Omega-3 fatty acids may slow ageing of the brain. Older
adults who supplement their diets with EPA and DHA
have demonstrated greater cognitive function when
compared to those who don’t.
■ Omega-3 fatty acids may prevent asthmatic mothers from
passing it on to their offspring.
■ People who do not like fish can get the omega-3 fatty
acids they need for optimal health from fish oil
supplements.
FAST FACTS ABOUT SALMON OIL PLUSTM
It has long been known and proven that omega-3 fatty acids play critical roles in the human diet. In particular,
two omega-3 fatty acids found in fish oil, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid)
have been well researched.
Today the latest scientific research not only continues to validate the important roles of EPA and DHA in
human health, but it has also shown that there is a whole family of omega-3 fatty acids, a total of eight in all,
which contribute to optimal human nutrition. This critically important chain of dietary omega-3 fatty acids
starts with ALA (alpha linolenic acid) and ends with DHA (docosahexaenoic acid), taking six important steps
along the way. Each is now known to have its own unique biochemistry and supporting “synergistic” role in
human omega-3 nutrition.
The United States Department of Agriculture suggests that all adults eat 2-3 servings of fish each week for
optimal health. Unfortunately, the problem for many adults is that they eat very little fish on a consistent
basis and rarely meet this important nutritional need. Large portions of the population go without getting
any broad spectrum omega-3 supplementation for weeks, sometimes months. Not to mention the fact that
much of the fish supply is suspect due to environmental contamination. Pregnant women, who have the
highest dietary needs for omega-3 fatty acids, ironically are instructed to limit their fish intake to one serving
per week, due to contamination risk.
GNLD solves the problem of inadequate omega-3 fatty acid intake with Salmon Oil Plus. Pure and
potent, Salmon Oil Plus provides a complete omega-3 profile of salmon oil with all eight members of the
omega-3 fatty acid family, assuring complete omega-3 supplementation in every dose.
SALMON OIL PLUSTM
Products – 4.06 P-1
ALA –
alpha-linolenic acid
SDA – stearadonic acid
ETA(3) – eicosatrienoic acid
ETA – eicosatetraenoicacid
EPA – eicosapentaenoicacid
HPA – heneicosapentaenoic acid
DPA – docosapentaenoicacid
DHA –
docosahexaenoicacid
MEET THE WHOLE FAMILY OF OMEGA-3 FATTY ACIDS
P-2 Products – 4.06
SALMON OIL PLUSTM
WHY GNLD SALMON OIL PLUS™?
■ Salmon Oil Plus is based on pure, natural salmon oil,
providing all the benefits of one of nature’s richest sources
of omega-3 fatty acids.
■ It includes UHPO3 –Ultra High Potency Omega-3 fatty
acids— an exclusive GNLD technology that boosts,
stabilizes, and standardizes specific, health-promoting
omega-3 fatty acid levels while maintaining the whole food
goodness of natural salmon oil.
■ It’s the first supplement of its kind to assure a standardized
amount of all eight members of the omega-3 family
involved in human nutrition.
■ It’s derived by “molecular differentiation” –leading edge
technology that selects specific nutrient molecules from
tuna, sardines, and anchovies, while eliminating or reducing
others, delivering unsurpassed potency, purity, and
consistency.
■ It’s safe, with no risk of accumulated toxins. Only the finest,
top quality, health-screened, disease-free fish selected for
human consumption are used. All sources are screened for
more than 160 potential contaminants with an allowable
detection limit of ZERO.
■ Potency guaranteed to deliver 460 mg EPA, 480 mg DHA,
50 mg DPA, and 80 mg mixed omega-3 fatty acids with
every 3-capsule serving.
■ No hidden vitamins A or D.

Salmon oil + with omega3

WHY SUPPLEMENT WITH FISH OIL RICH IN
OMEGA-3 FATTY ACIDS?

■ Fatty fish is the richest source of healthful omega-3 fatty
acids, but most of us do not eat the 2-3 servings per week
that experts recommend for optimal health.
■ Supplementation has been proven to be an effective means
of increasing dietary omega-3 fatty acids.
■ Omega-3 fatty acids support optimal function of body
tissues and organs, notably the heart, blood vessels, brain,
nerves, eyes, skin and joints.
■ Omega-3 fatty acids may prohibit overproduction of
substances that cause inflammation and contribute to
arthritis, menstrual pain, psoriasis, inflamed bowel and
other conditions.
■ Omega-3 fatty acids, crucial to the development of infant
brain and eyes, are naturally present in mother’s milk.
Infants, whose mothers consume foods rich in omega-3
fatty acids, have higher omega-3 fatty acid levels compared
to those whose mothers do not consume omega-3-rich
foods.
■ Omega-3 fatty acids may slow ageing of the brain. Older
adults who supplement their diets with EPA and DHA
have demonstrated greater cognitive function when
compared to those who don’t.
■ Omega-3 fatty acids may prevent asthmatic mothers from
passing it on to their offspring.
■ People who do not like fish can get the omega-3 fatty
acids they need for optimal health from fish oil
supplements.
FAST FACTS ABOUT SALMON OIL PLUSTM
It has long been known and proven that omega-3 fatty acids play critical roles in the human diet. In particular,
two omega-3 fatty acids found in fish oil, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid)
have been well researched.
Today the latest scientific research not only continues to validate the important roles of EPA and DHA in
human health, but it has also shown that there is a whole family of omega-3 fatty acids, a total of eight in all,
which contribute to optimal human nutrition. This critically important chain of dietary omega-3 fatty acids
starts with ALA (alpha linolenic acid) and ends with DHA (docosahexaenoic acid), taking six important steps
along the way. Each is now known to have its own unique biochemistry and supporting “synergistic” role in
human omega-3 nutrition.
The United States Department of Agriculture suggests that all adults eat 2-3 servings of fish each week for
optimal health. Unfortunately, the problem for many adults is that they eat very little fish on a consistent
basis and rarely meet this important nutritional need. Large portions of the population go without getting
any broad spectrum omega-3 supplementation for weeks, sometimes months. Not to mention the fact that
much of the fish supply is suspect due to environmental contamination. Pregnant women, who have the
highest dietary needs for omega-3 fatty acids, ironically are instructed to limit their fish intake to one serving
per week, due to contamination risk.
GNLD solves the problem of inadequate omega-3 fatty acid intake with Salmon Oil Plus. Pure and
potent, Salmon Oil Plus provides a complete omega-3 profile of salmon oil with all eight members of the
omega-3 fatty acid family, assuring complete omega-3 supplementation in every dose.

SALMON OIL PLUSTM
Products – 4.06 P-1
ALA –
alpha-linolenic acid
SDA – stearadonic acid
ETA(3) – eicosatrienoic acid
ETA – eicosatetraenoicacid
EPA – eicosapentaenoicacid
HPA – heneicosapentaenoic acid
DPA – docosapentaenoicacid
DHA –
docosahexaenoicacid

MEET THE WHOLE FAMILY OF OMEGA-3 FATTY ACIDS
P-2 Products – 4.06
SALMON OIL PLUSTM
WHY GNLD SALMON OIL PLUS™?
■ Salmon Oil Plus is based on pure, natural salmon oil,
providing all the benefits of one of nature’s richest sources
of omega-3 fatty acids.
■ It includes UHPO3 –Ultra High Potency Omega-3 fatty
acids— an exclusive GNLD technology that boosts,
stabilizes, and standardizes specific, health-promoting
omega-3 fatty acid levels while maintaining the whole food
goodness of natural salmon oil.
■ It’s the first supplement of its kind to assure a standardized
amount of all eight members of the omega-3 family
involved in human nutrition.
■ It’s derived by “molecular differentiation” –leading edge
technology that selects specific nutrient molecules from
tuna, sardines, and anchovies, while eliminating or reducing
others, delivering unsurpassed potency, purity, and
consistency.
■ It’s safe, with no risk of accumulated toxins. Only the finest,
top quality, health-screened, disease-free fish selected for
human consumption are used. All sources are screened for
more than 160 potential contaminants with an allowable
detection limit of ZERO.
■ Potency guaranteed to deliver 460 mg EPA, 480 mg DHA,
50 mg DPA, and 80 mg mixed omega-3 fatty acids with
every 3-capsule serving.
■ No hidden vitamins A or D.

Omega 3

Omega-3 Fatty Acids:
New studies show greater
powers while reaffirming what we already knew
The importance of omega-3 fatty acids to health and vitality
continues to be solidified as researchers investigate actions and
benefits not previously understood or even anticipated. It’s
becoming more apparent all the time that the amount of omega-
3’s in the diet directly effects all our cells and tissues and the
organs and systems they make up. In addition to being critical
components of the structure of our bodies they are also being
tied more and more to many functions. Here is some new
research worth knowing.

Omega-3 and Heart Health—
The link is now stronger The importance of omega-3 fatty acids to human health first
appeared as benefits to the heart. They were initially identified as
heart-health protectors that helped keep cholesterol balanced,
triglycerides low, and blood flow easier through veins and arteries.
Decades of research has proven there’s much more to them
than that. They are now known to play key roles in the structure
and function of the heart and the veins and arteries that make
up the entire cardiovascular system. Just how powerful omega-3
fatty acids are for heart health was driven home in a review
article published in the American Journal of Clinical Nutrition
(Vol. 84, pp. 5-17; July 2006). Researchers looked at a total of 43
studies. Those that made up the largest groups, more than
340,000 participants, reported “significant reductions” in risks to
heart health, making a large step forward toward greater assurance
of benefits. One study reported that an 850 mg dose of
omega-3 fatty acids (EPA & DHA) resulted in a 21% reduction
in death from all causes; a 35% reduction in cardiac death and a
45% reduction in sudden death. In their conclusion the
Columbia University researchers stated, “We believe that the
body of evidence is strong enough to suggest that in the United
States, certainly, and in other countries where omega-3 fatty acid
consumption is low, public health initiatives are needed to
increase intakes.”

Different omega-3 fatty acids give different heart-health benefits
In the August 2006 issue of the European Journal of Clinical
Nutrition (Vol. 60, pp. 978-984) researchers reported that though
the well known omega-3 fatty acids EPA and DHA had proven
heart health benefits, others, including ALA are being discovered
as important as well.

NEWS YOU CANUSE
ALA by itself is not the answer for humans
Alpha linoleic acid (ALA) is the primary building block for
other omega-3 fatty acids in both plants and animals. Plant
sources such as flax seed oil have been touted as omega-3
sources for years. In an editorial in the July 2006 issue of the
American Journal of Clinical Nutrition titled “Omega-3 Fatty
Acids and Cardiovascular Disease: Navigating Toward
Recommendations” researchers pointed out that “accumulating
data reaffirms that the EPA and DHA precursor ALA is inefficient
and much less efficacious” in humans. The reason is the
human body finds it very difficult to convert ALA into the seven
other omega-3’s the body makes and uses.
DPA—A powerful omega-3 fatty acid that is finally
getting the recognition it deserves
DPA, docosapentaenoic acid, has been a focus of attention for
only a few years, but what’s been learned is critical to long-term
diet and health. Researchers publishing in the journal
Circulation (vol.102; pp 2677-2679, 2000) showed that DPA /
DHA is more important than EPA / DHA in terms of
cardiovascular protection.
Making sure our nutritional supplements deliver whole families
of nutrients found within the food supply and present in
Nature’s blueprint for human nutrition has been a hallmark of
GNLD nutritional supplement success for decades.Whether it
has been to supplement all of the lipids and sterols from whole
grains, all of the flavonoids found with vitamin-C, or all of the
carotenoids from fruits and vegetables, dedication to this philosophy
has provided product performance that has become a
standard for science and industry. The recent introduction of
Salmon Oil Plus™ and the leading edge technologies that
make it the first complete Omega-3 supplement, delivering
standardized amounts of all eight omega-3 fatty acids involved
in human nutrition—including DHA, DPA and EPA—is just
another example.
Continued on page 2.
Volume #015 2006 U.S.A. & Canada
The whole family of Omega-3 Fatty Acids
2
Continued from page 1.
Don’t overlook minerals!
Though the research on whole foods—including whole grains,
fruits, vegetables, and fish—may currently overshadow studies
on minerals, much important new research is happening. Here
are some examples:
Magnesium: Is it an anti-inflammatory mineral?
Research published in the journal Nutrition Research (vol. 26, pp
193-196) indicates that it is. Using a blood chemistry marker
associated with heart disease and inflammation known as
C-reactive protein (CRP) researchers showed that magnesium
has anti-inflammatory actions in the body. Elevated CRP is a
consistent indicator of chronic inflammation because it is one of
the bodies “signaling molecules.” The higher and longer the
inflammation exists, the higher the CRP values. “Previous
research has indicated that dietary magnesium may be a key
component in the association between diet and inflammation”
proffers lead study author and Medical University of South
Carolina professor Dana King. “The key finding in this study is
that magnesium intake from supplements has an impact on the
likelihood of having elevated C-reactive protein.” People with
dietary magnesium intake below the RDA were found to have a
40% higher risk of elevated CRP.
Zinc is an anti-inflammatory mineral too!
Because zinc has long been known as an important building
block of natural antioxidant enzymes made in the body, such as
glutathione, peroxidase, and super oxide dismutase, it is thought
of as a “protector mineral.” Two recent studies further support
zinc’s critical importance. The September 2005 issue of the
Journal of Nutrition (vol.135, pp. 2114-2118) reported that zinc
deficiency was associated with increased risk of cardiovascular
disease through inflammation. New research published online in
the March 2006 issue of the journal Free Radical Biology in
Medicine (doi: 10.1016/j.freeradbiomed.2006.03.017) further
supports the oxidation/inflammation risk of deficiency.
Calcium: a possible key regarding hypertension and
pre-eclampsia risk during pregnancy
A large scale review of studies of calcium intake and risk of
hypertension and pre-eclampsia during pregnancy suggests this
is an important discussion for women to have with their
obstetrician. The review, published in the Cochrane Database of
Systematic Reviews (2006, issue 3), quotes lead author Dr. G.
Justus Hofmeyr, “The findings of the review are that calcium
supplementation reduces the risk of hypertension for pregnant
women who have inadequate dietary calcium.” In support of
these findings, independent pre-eclampsia expert Dr. John
Repke, Chairman of Obstetrics and Gynecology at Penn State
University College of Medicine commented “Calcium supplementation
may be of some benefit in reducing morbidity
(death) associated with pre-eclampsia, and it does no harm.”
Depleted soils and industrialized farming have combined to
reduce the mineral content of many foods—a fact previously
reported in GNLD’s News You Can Use (Volume 13, 2006). The
importance of minerals to health, vitality and longevity has
been a core concept in the GNLD product line for decades.
Minerals are a key link in the Chain of Life and assuring
deficiencies don’t exist is a smart health move for all. GNLD
offers several choices for those wanting assurance of a healthy
abundance of dietary minerals each day. Chelated Cal-Mag®,
Chelated Zinc and MultiMin with Chelates all provide potency,
purity and our exclusive double amino acid chelation technology
to optimize absorption. Vitality Calcium Plus provides a
comprehensive bone-mineral complex.
More research about Phyto-nutrition!
Whole tomato extracts are better than lycopene
alone
Tomatoes—and their active components—have received lots of
attention for their link to prostate cancer prevention. This attention
has inspired several companies to market pure lycopene
products. New research shows that these “now with Lycopene”
products may not be as good as the advertising suggests. A
review by researchers from the University of California,
Oklahoma State, and the Texas Women’s University considered
the results of several clinical trials conducted between 1998 and
2006 and showed that lycopene alone is not what is needed. A
whole tomato concentrate that provides not just lycopene, but
all its forms and all its supporting carotenoids is a much more
prudent and appropriate choice. Researchers concluded that
while there is proof of “convincing antioxidant and
anticarcinogenic effects” for lycopene in tomatoes or as a tomato
concentrate, “in vivo data (data from living systems) on the
effects of pure lycopene is lacking.”(European Journal of Clinical
Nutrition; doi: 10.1038/sj.ejcn.160Z510).
Lutein and zeaxanthin—new links to cardiovascular
health!
The first research to show a positive connection between the
carotenoid lutein to heart health came in a 2001 issue of
Circulation (vol. 103, pp. 2922-2927). Now researchers from
Sweden have found yet another strong link. Publishing in the
February 2006 issue of Nutrition, Metabolism and Cardiovascular
Disease (doi: 10.1016/numecd.2006.02.006) the researchers
pointed out that people suffering from coronary artery disease
are consistently found to have low levels of the carotenoids
lutein, zeaxanthin, and beta cryptoxanthin. Conversely, they
found that the healthy persons in the control group had significantly
higher levels of these carotenoids in their blood. They
think it’s connected to immune function because of higher levels
of natural killer cells (NK cells) in the people with higher levels
of these carotenoids. “This finding suggests a specific link
Continued on page 3.
3
SAB HAS THE ANSWERS:
Q. Is "molecular differentiation" the same as “molecular
distillation” that is commonly used in the industry?
A. No, these two terms refer to processes which are very different. The
exclusive GNLD technology used for Salmon Oil Plus called “molecular
differentiation” allows us to select and concentrate specific omega-3
molecules while at the same time identifying, extracting and eliminating
other non-omega-3 fatty acid molecules that play roles only in
taste, odor or color. Molecular distillation focuses on isolating and
concentrating only a single molecule.
Q. What is Neo-Plex Concentrate and why does GNLD
use it in their products?
A. GNLD’s Neo-Plex Concentrate provides all the nutritional elements
found in whole oranges including the juice, rind and pulp, vitamin
C, bioflavonoids, flavedo, mesocarp, endocarp and protopectins
and other naturally occurring factors to enhance the absorption and
utilization of vitamin C. Research shows vitamin C stays in the body
longer and is utilized better when consumed with natural, whole food
components.
Q. Which source of calcium is the best to take?
A. When it comes to calcium sourcing, the key issues for comparison
of calcium products are purity, consistent quality, dissolution time and
absorption—factors in which all GNLD products excel. GNLD has four
different calcium products.
Chelated Cal-Mag® uses our unique double amino acid chelation
process for improved absorption. Each serving of Cal-Mag provides
300 mg of calcium plus 150 mg of magnesium and is available in either
tablets or capsules. Cal-Mag capsules also provide 400 IU of vitamin D.
Vitality Calcium Plus™ is more than a calcium product; it is a comprehensive
mineral complex designed to support the development and
maintenance of strong, healthy bones. Each serving contains multiple
sources of calcium plus key minerals which are critical to the process of
bone development. It is also lactose free.
Neo-Cal™ is a chewable, multiple sources calcium supplement with
added vitamin C, magnesium and natural betaine HCl to support
digestion, absorption and utilization.
Q. What can I take to relieve the pain and discomfort of
arthritis?
A. Peer-reviewed scientific studies conducted around the world have
demonstrated the benefits of omega-3 fish oil supplements in alleviating
tenderness and inflammation in the joints, and can relieve the
morning stiffness that makes arthritis so painful. Any one of GNLD’s
omega-3 products: Salmon Oil Plus, Salmon Oil, or Omega III
Concentrates can deliver the nutritional abundance of natural omega-3
fatty acids to support health and comfort.
Q. If I take Carotenoid Complex™, why should I take
Cruciferous Plus™ and Flavonoid Complex™?
A. Three of the primary fruit and vegetable phytonutrients groups
associated with health protection and disease prevention are
carotenoids, flavonoids and cruciferous. These products have different
functions within the body. Science has shown that these three different
nutrient groups protect us and our cells in different, yet
complementary, ways. Carotenoids protect the lipids in the blood and
cell membranes; flavonoids protect the watery portions inside and outside
of our cells; cruciferous nutrients protect the cell as a whole from
the negative effects of certain carcinogens.
Research has shown that the vast majority of people do not get enough
fruits and vegetables in their diet. Carotenoid Complex, Flavonoid
Complex and Cruciferous Plus are complete whole-food supplements
formulated to deliver an abundance of these important protector nutrients.
When taken together, they offer the most complete phytonutrient
protection possible!
Q. Would the soy found in Cruciferous Plus interact
negatively with someone who had breast cancer?
A. There is no evidence to suggest that any of GNLD’s products which
contain soy would interact with the body in a negative manner. Intake
of soy products has actually been linked to a decreased risk of breast
cancer. Soy contains isoflavones which have been shown to provide
some protection against breast cancer.
GNLD’s Cruciferous Plus is an exceptional whole-food product that
provides the density and diversity of the phytonutrients found in an
optimal serving of cruciferous vegetables. Additionally, Cruciferous Plus
provides important related nutrients, including sulforaphane, isothiocyanates
and indole carbinols.
between certain carotenoids, oxidative stress, and immune perturbation
(imbalance) in CAD,” said lead researcher Caroline
Lidebjer from the University Hospital at Linkoping, Sweden.
More evidence of lutein and eye health
Researchers showcased findings from a 48-week long intervention
trial that used supplemental doses of the carotenoid lutein
to measure preservation of visual function with patients with
retinitis pigmentosa (RP). Published in the journal
Ophthalmology (BMC Ophthalmology 2006, 6:23), researchers
reported that the results of their placebo-controlled study
showed that lutein supplementation was preventive.
“Comparing the development of vision measures against the
natural loss expected to occur over the course of the 48 weeks,
most measures showed reduced decline, and these reductions
were significant for normal illumination.”
Complete Carotenoid Phyto-nutrition—the role of plant
derived nutrients in human nutrition—has been a cornerstone
of GNLD supplementation since the beginning, 1958, with the
whole-grain lipid and sterol supplement Tre-en-en®. The introduction
of Carotenoid Complex™ in 1992 resulted from more
than a decade of research and development that focused on
identifying, concentrating, and extracting complete and intact
the many carotenoids found in whole foods within the human
food chain. This was a daunting technological feat that resulted
in not just a patent, but peer-reviewed publications and USDA
researcher investigations that proved Carotenoid Complex protects
our hearts, our cells, and boosts immune capacity, including
the body’s first line of defense against disease, natural killer
cells (NK Cells). It is the first and only whole food supplement
to provide the complete family of carotenoids, including; alpha
& beta carotene, lycopene, lutein, zeaxanthin, beta cryptoxanthin
and at least nine others. (www.carotenoidcomplex.com)
Continued from page 2.
Continued on page 4.
PLACE
STAMP
HERE
of cancer-related genes can be influenced by the chemopreventive
compounds in the things we eat.” states lead researcher
Ah-Ng Tony Kong, professor of Pharmaceutics in the Ernesto
Mario School of Pharmacy at Rutgers.
Both Flavonoid Complex™ and Cruciferous Plus™ are
broad-spectrum formulas that supplement a wide range of
phytonutrients found and needed in the human diet.
Flavonoid Complex is derived from ten natural fruit sources
and delivers the broad flavonoid profile they provide.
Cruciferous Plus comes from nine cruciferous and related fruit
and vegetable sources, including broccoli for the active
cruciferous compounds sulforaphane and indole carbinol.
Both Flavonoid Complex and Cruciferous Plus have been
tested to National Cancer Institute protocols and proven
biologically effective.
Factoid:
Spinach is a great source of the carotenoids lutein and zeaxanthin;
both important for eye health and vision longevity. But did you
know that spinach was probably first eaten by people living in the
Middle East? And they probably were eating it hundreds of years
before Europeans! Spinach is also related to a group of plants called
“goosefoots” because of the shape of their leaves.
Factoid:
Broccoli has been around for over 2000 years and was a favorite
food of the ancient Romans. The average American eats only about
four and one half pounds a year. That’s less than 1/5th of an ounce
a day or only about 1/20th of the amount recommended as the
minimum daily target. Does that tell you something?
NASA research speculates Flavonoids will protect
future astronauts on long space flights.
Scientists at Tufts University and the University of Maryland
have been experimenting with the effects of the high level radiation
astronauts will be exposed to on flights to other planets.
Their initial conclusions, published on line in the journal
Neurobiology and Aging (doi:10.1016/j.neurobiolaging.
2006.05.031) are that the flavonoids found in fruits like
strawberries and blueberries are neuro-protective, with specific
flavonoids protecting specific brain tissues or regions. “It
appeared that the antioxidant diets and the different polyphenols
(flavonoids) in these fruits might act in different brain
regions to produce their beneficial effects.” As is typical in the
broad array of fruits found in Nature’s plan for human
nutrition, many inter-related and likely synergistically acting
flavonoids are needed in the diet. “These findings suggest that
multiple mechanisms may be involved in the beneficial effects of
high antioxidant fruits—on ageing as well as radiation.”
Broccoli, cauliflower and genetic cancers
Rutgers University researchers have just published new data
showing that broccoli, cauliflower and other cruciferous vegetables
have natural ingredients that may reduce the risk of developing
hereditary cancers. The natural ingredient they’re talking
about is sulforaphane and it’s not the first time it’s been shown
to have anticancer properties.What is important about this
study is the genetic connection. People with hereditary cancer
risk are essentially genetically predisposed to the disease. This
research, published online in the August 2006 journal
Carcinogenesis, advises that the risk is not, however, beyond control.
“Our research has substantiated the connection between
diet and cancer prevention, and it’s now clear that the expression
Continued from page 3.

omega 3 & 6

Omega-6 and omega-3 fatty acids (FAs) both play an important role in health. Unfortunately, a lot of people have the perception that we need to take supplements of both groups of fatty acids. This is not strictly true.

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Omega-6
What we tend to forget is that most people who eat a western diet that contains poly- and monounsaturated margarine and cooking and salad oils, get an overdose of omega-6 FAs. If you use margarine and sunflower oil in your kitchen, then the chances are good that you are getting more than enough omega-6. In fact you may be getting too much.

A complicated relationship
Now how is it possible to “Get too much of a good thing like omega-6?” The problem with these essential fatty acids, is that we not only have to make sure that we include them in our diets, but that the amounts we eat are balanced. And what does this mean?

Researchers have discovered that the so-called omega-3 to omega-6 ratio should be about 1/5 for optimal health. This means that we must make sure that we eat 1 g of omega-3 for every 5 g of omega-6. Seeing that human intake of omega-6 in western countries has increased dramatically with the introduction of margarine and salad and cooking oils, most of us get more than enough omega-6. The general intake of omega-3, which is mainly found in fish and fish oils, has however, decreased just as dramatically over the years so that we hardly ever achieve the ideal ratio of 1 to 5. In many diets the ratio is 1 to 20 or even 40. It is, therefore, important to make sure that we eat more omega-3.

The reason why we need a 1 to 5 balance in omega-3 and omega-6 intake, is that these essential fatty acids compete with each other in our bodies for enzymes. If you eat too much omega-6 and not enough omega-3, only omega-6 will be metabolised and your body won’t be able to use the omega-3 fatty acids. Such an imbalance can cause all kinds of diseases.

Omega-3 and health
If you eat sufficient omega-3 FAs, you will be protected against the following diseases and conditions:

• Heart disease - omega-3 FAs lower the risk of developing heart disease and can reduce the risk of dying from a heart attack by 30%
• Blood clots - omega-3 FAs make blood less sticky and prevent blood clots
• Hypertension - omega-3 FAs lower blood pressure
• High blood fat levels - omega-3 FAs lower ‘bad’ cholesterol and triglyceride levels in the blood
• Breast cancer - high omega-6 and low omega-3 FA levels may predispose women to develop breast cancer
• Colon and bowel cancer - omega-3 FAs may prevent colon cancer
• Rheumatoid arthritis - research results indicate that omega-3 FAs may help to prevent this crippling disease
• Crohn’s disease - there is some indication that the omega-3 FAs may help to alleviate chronic inflammatory bowel disease

In addition, omega-3 FAs are important for the normal development of the brain, nervous system and vision in infants before, and during the first year after birth. Omega-3 FA supplementation during pregnancy and even in breast-fed infants is advisable.

Although research into the role of omega-3 FAs in psychiatric conditions, such as depression and schizophrenia, is still in the early stages, some studies have shown promising results.

Sources of omega-3 fatty acids
More and more scientific evidence points to the fact that omega-3 FAs are important for human health and normal development. It is becoming increasingly clear that modern man eating a western diet with a low fish content, is exposed to omega-3 FA deficiency and an imbalance in the omega-3:omega-6 ratio.

The following foods and supplements are rich sources of omega-3 FAs:

• Fish - mackerel, herring, salmon, tuna, sardines, anchovies, trout and sturgeon
• Fish oils - cod liver oil, salmon oil, tuna fish oil
• Salmon oil capsules
• Plant sources- flaxseed, canola, walnut and soya oils
• Omega-3 enriched foods - eggs, milk and bread

If you suspect that you are not ingesting sufficient omega-3 FAs, make a plan to eat fish at least twice, if not three times a week. You can also switch to using flaxseed, canola or soya oils and start using enriched foods, such as Omega-3 enriched eggs, milk and bread. If you are at risk of any of the above-mentioned diseases, regular intake of salmon oil supplements is advised. - (Dr I.V. van Heerden, DietDoc)

Trust Yourself

In any relationship trust is the first thing to leave and the last to return. And if you recognize that the most important relationship is with yourself, then perhaps it's time to start some trust building close to home. Make and keep a promise or a commitment to yourself, however small - in fact, start very small! Make one and keep one today, and then notice the surge of inner power as a result. See how much more you like yourself as a result. Trust is being built.

Choices

Life is all about choices. When you cut away all the junk, every situation is a choice. You choose how you react to situations. You choose how people affect your mood. You choose to be in a good mood or bad mood. The bottom line: It's your choice how you live life.

Something of interest

Too much stress, too much spicy food, and you may be headed for an ulcer - that was the way the thinking used to go.

Peptic ulcers are open sores that develop on the inside lining of your stomach, upper small intestine or esophagus. The most common symptom of a peptic ulcer is pain.

Not long ago, the common belief was that peptic ulcers were a result of lifestyle. Doctors now know that a bacterial infection or some medications - not stress or diet - cause most ulcers of the stomach and upper part of the small intestine (duodenum). Esophageal ulcers also may occur and are typically associated with the reflux of stomach acid.

Peptic ulcers are common, and oftentimes successful treatment of peptic ulcers takes just a few weeks.

I have been taking Acidophilis - what a difference it has made to my system and immunity.

www.yourday2day.co.za

Something of interest

Too much stress, too much spicy food, and you may be headed for an ulcer - that was the way the thinking used to go.

Peptic ulcers are open sores that develop on the inside lining of your stomach, upper small intestine or esophagus. The most common symptom of a peptic ulcer is pain.

Not long ago, the common belief was that peptic ulcers were a result of lifestyle. Doctors now know that a bacterial infection or some medications - not stress or diet - cause most ulcers of the stomach and upper part of the small intestine (duodenum). Esophageal ulcers also may occur and are typically associated with the reflux of stomach acid.

Peptic ulcers are common, and oftentimes successful treatment of peptic ulcers takes just a few weeks.

I have been taking Acidophilis - what a difference it has made to my system